glp 1 and ghrelin Targeting GLP-1, GIP & GCG in Obesity Type 2 Diabetes Research Hormonal Gut–Brain Signaling for the

Bariatric surgery works, but it is invasive and carries surgical as well as lifelong nutritional risks

Ozempic, a widely used medication for weight loss, has been linked to a range of adverse effects

Multi-omics results show that ALOX15 is the main mediator of phospholipid peroxidation, acting as an ignition point during the ischemia stage, igniting phospholipid oxidation and promoting cell ferroptosis

Lipofuscin is another pigment which increases in the myocardium, skeletal muscle, liver etc with increasing age.1 Lipofuscin is biochemically distinct from melanin and shows a characteristic autofluorescence.2 Non-aged related deposition of lipofuscin occurs in the melanosis coli (so-called "brown bowel syndrome") as described below, as well as in many other organs, such as the thyroid, oesophagus, and the gall bladder.1 This condition, whereby the normal pinkish colonic mucosa became diffusely infiltrated by dark pigmentation, was described as early as 1825