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According to the recent progress in research on the mechanism of intestinal microbial-derived IBS metabolites, further investigation into the production of gut microbiota-derived metabolites, which may in part underlie the pathophysiology of IBS, are urgently needed

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CD44/CD105 human amniotic fluid mesenchymal stem cells proliferate rapidly in vitro and can survive and proliferate for extended periods in the ovaries of a POF mouse model, suggesting they may also be a promising therapeutic option for POF [130]

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