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12,13 The activated MAP kinases stimulate transcriptional regulatory proteins and other kinases of protein and which is enhanced the inflammatory cytokine such as TNF-, IL-1, and MMPs production

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123,124 Feeding table scraps has been associated with canine obesity, 124 a greater than 3-fold increased risk of canine diabetes, 125 and a 26-fold increased risk of pancreatitis (inflammation and self-destruction of the pancreas that can range in severity from mild to fatal)