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While moderate weight reduction may yield metabolic benefits, rapid or sustained weight loss is frequently associated with decreased bone mineral density, deterioration of bone microarchitecture, and heightened fracture risk

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Patients who suffered CS (281 hypertensives were with ischemic stroke, 25 hypertensives suffered from hemorrhagic stroke) were recruited at the Neurology Clinics of Kursk Emergency Medicine Hospital between 2007 and 2010