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Marcombe S, Fustec B, Cattel J, Chonephetsarath S, Thammavong P, Phommavanh N, et al

Removal of agonists or binding of antagonists in in-vitro conditions allows the receptor transition to resting/closed state by rearranging LBD to a dimeric state, which leads to re-positioning of the linkers between LBD and TM 31