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I invited Paul Stamets, dsc, and Heather Zwickey, phd, to write a commentary on mushrooms to help us better understand these very interesting agents

Harnessing nanomedicine to overcome the immunosuppressive tumor microenvironment

A wide range of non-motor manifestations, including hyposmia or anosmia, gastrointestinal disturbances like chronic constipation, rapid eye movement (REM) sleep behavior disorder, autonomic dysfunction, mood changes like depression and anxiety, and progressive cognitive impairment, account for a significant portion of the disease burden [3]

For many users, this convenience outweighs potential advantages of alternative treatments