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These studies span dose ranges that encompass probable human exposures

Effect of semaglutide on primary prevention of diabetic kidney disease in people with type 2 diabetes: a post hoc analysis of the SUSTAIN 6 randomized controlled trial

Interestingly, TFR1 had been previously identified as the major cell surface receptor for IgA1 binding in renal mesangial cells and its overexpression has been correlated with the proliferation of mesangial cells in IgAN patients [269,270,271]

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