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The findings tentatively indicate that the peptide might have contributed to a potential weight gain and a potential uptick in the overall tibial and vertebral BMC (bone mineral content) as observed via DXA, in contrast to the control set

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By using bioinformatics tools like Seurat, researchers can normalize data, perform dimensionality reduction, identify spatial patterns of gene expression, and integrate with single-cell data

However, like metformin, thiozonidediones are known to present with various side effects (DeFronzo et al., 2016), and their long-term protects effects against deteriorated metabolic function is not proven