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For example, non-steroidal anti-inflammatory drugs often prescribed for pain management have been associated with gastrointestinal disturbances, raising concerns about their long-term use in ME/CFS patients who already report high levels of gut-related issues [185, 186]

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A 2025 UCSF open-label pilot in Parkinsons disease, the first test of a psychedelic in a neurodegenerative disease, found that two sessions improved mood, cognition, and motor symptoms for weeks to months, with a larger randomized trial now under way