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Niclosamide can readily revert to its most stable form, and so reduce its solubility However, if, and when, precipitated or present as a particulate material, (e.g., micronized or surfactant- or protein- or polymer-stabilized microparticles as observed in our provisional patent work (48)), the amount of niclosamide in aqueous solution is determined by the nature of the crystalline or amorphous material that the local aqueous solution is in equilibrium with, or is moving towards

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