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Administering UA at the onset of SCI can inhibit various pathological changes in the spinal cord, including systemic tissue injury, nitrotyrosine production, lipid peroxidation, poly(ADP-ribose) polymerase activation, and neutrophil infiltration [45]

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Blood J Am Soc Hematol 119(24):57725781 Misiewicz M, Dery MA, Foveau B, Jodoin J, Ruths D, LeBlanc AC (2013) Identification of a novel endoplasmic reticulum stress response element regulated by XBP1