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This is the most mechanistically coherent use case for oral delivery because the peptide acts locally before it is degraded
Its high haloranon content makes it slippery, reducing friction between various structures, and allowing nerves and blood vessels to glide smoothly
The Lau et al
We refer commenters to the testing results in this rule, as well as the results calculated using the July 2023 Overall Star Rating as reported in the CY 2025 OPPS/ASC final rule with comment period (89 FR 94514 through 94521) which produced similar findings
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