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When levels drop, the liver may become more susceptible to oxidative damage

Hydroxocobalamin injections can also treat pernicious anemia

However, angiogenesis is not universally beneficial in all biological settings

A large GWAS study that included 457,690 individuals (121,289 individuals with CAD and 63,495 individuals with myocardial infarction) showed that genetically determined elevated serum UA level was associated with the increased risk of CAD [OR =1.10 (95% CI: 1.061.15)] and myocardial infarction [OR =1.12 (95% CI: 1.071.18)]