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For example, the Lactobacillus rhamnosus GG strain may modulate intestinal immune cells to reduce the release of inflammatory cytokines (Li et al., 2020), whereas Bifidobacterium longum NCC3001 may exert direct effects on the central nervous system via the vagus nerve to enhance the synthesis of neurotransmitters such as -aminobutyric acid (Bercik et al., 2011)

The glucagon component distinguishes it from currently approved agents such as semaglutide and tirzepatide

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[Abstract]2023 Oct 28:315:116664