Considering a high contribution of sulfation in acetaminophen metabolism, the importance of oxidation in APAP toxicity and of glutathione in APAP detoxification, more studies are needed to establish the relationship between polymorphisms in SULT , GST and CYP genes, and interindividual variability in response to acetaminophen
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Sedentary ME/CFS, and healthy control subjects were recruited from websites, word of mouth, fliers, newspaper and online advertisements, and personal contacts in clinics and support groups
