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Long-Term Considerations For most individuals, the benefits of these medications are contingent on continued use
It falls under the category of glucagon-like peptide-1 (GLP-1) receptor agonists, meaning it binds to GLP-1 receptors and stimulates insulin secretion while inhibiting glucagon release
That combination is why so many people on Ozempic, Wegovy, or Zepbound feel oddly tired, headachy, crampy, or constipated even when the scale is moving
Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and decreased appetite, which are generally mild to moderate and tend to diminish over time
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