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Zileuton, an FDA-approved oral medication for treating asthma, is an ALOX5 inhibitor that exerts neuroprotective effects by blocking ALOX5-mediated glutamate toxicity and ferroptosis in HT22 cells, a mouse hippocampal cell line [301]

As with any peptide, the diluent is added gently down the vial wall and the vial is swirled rather than shaken, because agitation can degrade peptide structure

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Supplementary material The Supplementary Material for this article can be found online at: References 1 AnH.ZhaiZ.YinS.LuoY.HanB.HaoY