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They are intended to stimulate the immune system to fight an existing disease rather than avoid sickness [215]

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Taken together, Akkermansia muciniphila may exert a double-edged sword effect on the homeostasis of the gut-joint axis through changes in its abundance: at moderate levels, it enhances intestinal barrier function and inhibits inflammation, while dysbiosis (either excessive or insufficient abundance) exacerbates the pathological progression of OA by disrupting mucus layer integrity and promoting toxin translocation

With muscle loss comes a loss of strength and function, increasing the risk of falling over (and not just when we're older) and making everyday tasks (like climbing the stairs) feel a lot harder