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Simply dieting or exercising after stopping semaglutide proved insufficient to maintain the weight loss achievedsuggesting that the medication's effect on appetite regulation is fundamentally different from willpower-based approaches

This study showed a significant association between GLP-1 RA treatment and an 98% increased risk of any psychiatric disorders

Accompanying symptoms frequently include: Nausea and vomiting that may be persistent and provide little relief Abdominal tenderness and distension , with the abdomen feeling swollen or tight Fever and tachycardia as systemic inflammatory responses develop Loss of appetite and an inability to tolerate oral intake In severe cases, signs of systemic illness such as jaundice, confusion, or shock Patients taking Ozempic should be counselled to recognise these warning signs

So, uh, there is something to be said about this inflammatory component