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The following antibodies were used in the present study with dilutions in parentheses: From Cell Signaling Technology, Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody (1:3000) #9101, p44/42 MAPK (Erk1 Antibody (1:5000) #9102, Phospho-Smad3 (Ser423/425) (C25A9) Rabbit mAb (1:1000) #9520, Phospho-p70 S6 Kinase (Thr389) Antibody (1:1000) #9205, Phospho-S6 Ribosomal Protein (Ser235/236) Antibody (1:1000) #2211, Phospho-4E-BP1 (Ser65) Antibody (1:1000) #9451, Vimentin (R28) antibody (1:1000) #3932