Metabolomics is particularly valuable for metabolic disorders such as CVDs, where function and metabolism are inextricably linked at both the systemic and cardiac levels 25
Additionally, dehydration which can occur secondary to the gastrointestinal side effects of GLP-1-based therapies, such as nausea and vomiting may compound the chronotropic effect by triggering a compensatory reflex tachycardia
Dailey DL, Vance CGT, Van Gorp BJ, Johnson EM, Post AA, Chimenti RL, Vance KG, Franck C, Sault J, Yarasir E, Reisinger HS, Anderson A, Anderson J, Capelle R, Crouch A, Donatelle J, Kaster D, Kepros T, Nicklies E, Rein B, Worth R, Balinski M, Lafontant DE, Slade EJ, Jiang F, Ecklund D, Neill-Hudson T, Koepp M, Costigan M, Spencer M, Archer KR, Zimmerman BM, Bayman EO, Crofford LJ, Sluka KA
3 The gradual pace made everything feel easy and manageable