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Human CD4 + Th2 clones specific for the house dust mite allergen Der p I can be rendered non-responsive to subsequent Der p I challenges by incubating them with Der p I- derived peptides, representing the relevant minimal T-cell activation inducing epitopes, in the absence of professional APC (Yssel et al., 1994)

Glutathione biosynthesis occurs in several, but not in all eukaryotic cell types through a well-coordinated and feedback-modulated process that needs one essential amino acid, cysteine, and two others, glutamic acid and glycine, that most cells can synthesize themselves from the intermediates of core metabolism