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PLoS ONE 10 , e0134137 (2015)
In this population, prior early-life exposure has been associated with persistent structural alterations, including reduced gray matter volume in hippocampal regions implicated in memory processing, suggesting long-lasting consequences that may manifest or be exacerbated later in life ( Cannabis exposure has been associated with region-specific alterations in neural connectivity, particularly in brain regions with high CB1R density, including the medial temporal cortex, the temporo-parietal-occipital junction, and the hippocampus
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