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BMI thresholds still exist because clinical trials primarily studied patients meeting specific BMI requirements, and FDA indications and insurance policies are generally based on those populations

Research on pre-meal protein preloads shows they can lower how much you eat at the following meal and blunt blood-sugar spikes (research summary), and small studies on gelatin specifically have found increased fullness

It doesnt distinguish muscle from fat, and it doesnt account for waist circumference, which is a better predictor of metabolic health in most people than BMI alone 3

However, Thus, questions remain about what happens when individuals stop taking these medications