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Interestingly, the same results were not observed in healthy age-matched mice, as 6 weeks of progressive ladder-climbing RT (3 climbs, progression from 50% to 100%MCL, 5 times per week) decreased lipid peroxidation in the cerebral cortex but increased lipid peroxidation in the hippocampus (Feter et al., 2019)

Subsequently, for these data as well as the alpha diversity analyses, each treatment group (within each phylum or genus for the relative abundance data) was analyzed for normal distribution (ShapiroWilk test) and the data across groups were tested for homoscedasticity (BrownForsythe test)

LKB1 phosphorylates and activates AMP-activated protein kinase (AMPK), which functions as an energetic sensor, regulating glucose and lipid metabolism in response to alterations in nutrients and intracellular energy levels [7]

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