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The study found that CoQ10 monotherapy did not significantly reduce symptoms compared to a placebo, highlighting that a single nutrient may not be enough to overcome deeply entrenched mitochondrial dysfunction

While convenient, skipping pre-treatment labs can delay identification of underlying thyroid dysfunction, kidney impairment, or metabolic abnormalities that may influence medication safety and dosing

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23 Due to the superior efficacy of antioxidative enzymes in scavenging ROS compared to exogenous molecules, the antioxidative effects mediated by NRF2 are notably significant