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Neurocognitive peptides are signaling molecules that mimic or modulate the body's own neurotrophic factors, often acting more directly on neurons and synaptic structures

Based on the regulation of synaptic plasticity by neurexins and the exploration of the sustained antidepressant effect and material basis, this is also a new direction to expand the library of alternative agents for sustained antidepressant effect

NLRP3 inflammasome regulates release of IL-18 and IL-1 (pro-inflammatory cytokines) in macrophages and gets activated on receiving damage-associated molecular patterns (79)