Supplements impact the skin, positively or negatively, in one of two ways: altering the chemistry in one of our skin-organ axes (like the gut-skin axis, liver-skin axis, nervous system-skin axis, etc.) or traveling from our gut, into our blood, then to our skin where they directly impact the skin tissue itself or the skin microbiome
It was initially discovered to bind to actin, which is part of the cytoskeleton, and influence cell migration for wound healing.[ref] Thymosin beta 4 was initially isolated from the thymus in calves, which is why it was named thymosin
It is especially this kind of adipose tissue that is believed to drive a large part of the pathological effects of excess body weight ( The reductions in ROS and systemic inflammation, in combination with improvements in the other cardiometabolic parameters, are also thought to mediate the substantiated but so far formally unconfirmed kidney-protective effects of GLP-1 RAs, which may also directly or indirectly carry a HF-related benefit, considering that CKD is a prominent risk factor for HF (von Scholten et al., 2022)
J Thyroid Res 2023(1):5707120 ALshamrani SM, Safhi FA, Mobasher MA, Saleem RM, Alharthi A, Alshaya DS, Awad NS (2022) Antiproliferative effect of Clitoria ternatea ethanolic extract against colorectal, breast, and medullary thyroid cancer cell lines