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Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation

It immediately increased to a higher level until 4 h pi and then decreased to a minimum at 12 h pi , before slowly recovering

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Daily intraperitoneal administration of OEA to mice induces satiety and prevents weight gain, a feature that may be true of other GPR119 agonists (184, 188)