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Contact your provider promptly if you experience severe or persistent gastrointestinal symptoms while using both medications, including: severe diarrhea lasting more than 24 hours, signs of dehydration (decreased urination, dizziness, extreme thirst, dry mouth), persistent vomiting preventing adequate fluid intake, severe abdominal pain or cramping, or blood in stool

Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohns disease

doi:10.3389/fnins.2023.934341 77

When Taking Your Semaglutide Injection Early Is Reasonable Taking your semaglutide injection one day early is generally safe if you're shifting your permanent injection schedule forward (for example, moving from Wednesday to Tuesday every week)