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GLP-1 receptor agonists like semaglutide work by slowing stomach emptying and signaling fullness to your brainbut these effects stop within days of your last dose

however, whether GLP-1RAs increase the risk of pancreatitis remains controversial (11)

Le from US Dermatology Partners states, I tell my patients they need to wait for at least six months after starting semaglutide treatment or undergoing weight loss surgery to begin body contouring. This minimum waiting period addresses several safety concerns specific to GLP-1 users

For comparison, semaglutide 2.4 mg achieved 5.7 kg at 40 weeks in the head-to-head SURMOUNT-2 crossover data