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This helps in reducing errors during the procedures and also maintains the engagement of the patient participation in these studies
Melatonin has been shown to modulate the cell cycle of liver cancer cells via alterations in cyclin D1 expression and induction of G0/G1 arrest, which is mediated by upregulation of p53 and its downstream effector p21, resulting in inhibition of cyclin-dependent kinases (CDKs)
Chaudhary P, Janmeda P, Docea AO, Yeskaliyeva B, Abdull Razis AF, Modu B, et al
Clin Microbiol Rev 2003;16: 497516
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