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An observational study from January 2006-December 2023 found that of the 227, 866 individuals with AUD and comborbid obesity or type 2 diabetes studied, semaglutide and liraglutide were associated with a significantly lower risk of AUD hospitalization than those taking well-established AUD treatments (21) A systemic review from November 2024 showed that there was a significant reduction in substance use disorders in the 630 subjects prescribed either exenatide or dulaglutide for substance use disorder (22)