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Decanoic acid is able to modulate astrocyte metabolism directly, leading to activation of the astrocyte-neuron lactate shuttle and providing fuel to neighboring neurons in the form of lactate (130, 131)

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Mitochondria as a therapeutic target for aging and neurodegenerative diseases

Because Truveta Data provides the most complete, timely, and clean de-identified EHR data, including full patient medical records, notes, and images, linked with claims, SDOH, and mortality data for more than 100 million patients across the US, we can show the latest trends in these medications, including the early uptake in tirzepatide labeled for obesity (Zepbound), which was approved by the FDA in November 2023