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This review article discusses the potential antidepressant effects of GLP-1RAs, especially in the context of their action on the processes related to neuroprotection, inflammation, stress response, energy metabolism, gut-brain crosstalk and the stability of the gut microbiota

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In a model induced by repeated Brucella antigen injections, hippocampal atrophy was accompanied by reduced DG neurogenesis, increased granule-cell apoptosis, and decreased BDNF expression (Moriya et al., 2011)

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