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Lean muscle mass loss occurs proportionally with weight loss, highlighting the importance of resistance exercise and adequate protein intake to preserve muscle and bone health

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Among them, only the GLP-1R x GCGR dual agonist, Mazdutide, developed by Innovent Biologics/Eli Lilly, has completed clinical trials and is seeking market approval

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The trial involved 48 participants who randomly received semaglutide or a placebo

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