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In addition, and also via gut-mediated action, metformin enhances the release of glucagon-like peptide-1 (GLP-1)

Eichner, L

The mice were sacrificed on days 0, 5, 10, 20, and 30 after the start of HFD feeding and then liver tissues were collected

Researchers observed a selective stress-dampening effect of phosphatidylserine (400 mg for 4 weeks) on the pituitary-adrenal axis, including a substantial reduction in the increase in serum cortisol concentration, suggesting the potential for the treatment of stress-related disorders (Hellhammer 2004) References Abedon, Bruce et al