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We note that although the chondroprotective effects of metformin was clearly attenuated in Nrf2 KO mice, micro-CT analysis revealed some variability in trabecular bone parameters, including occasional increases in subchondral trabecular bone amounts in Nrf2 KO OA mice (Fig

Sections of the atheroma with a deteriorated fibrous cap are subject to rupture (Figures 4 and 5) (168,169)

289 In ovarian cancer, ACSS2 inhibition suppresses glycolysis and induces its nuclear translocation, activating a SIRT1/ATG5/ATG2B axis that promotes autophagy and reduces malignancy