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With higher potency and a better breakdown resistance, the second generation of copper peptides followed their predecessors, coming out in the early 1990s

SS-31 targets mitochondrial function, supporting cellular energy production that underlies all regenerative processes

Illustratively, in the mentioned laser-wound studies, human albumin solder supplemented with transforming growth factor (TGF)-1 only, but not with HB-EGF or bFGF, increased the early postoperative strength of laser-welded wounds (Poppas et al., 1996), even though the superpulsed CO 2 laser enhanced fibroblast replication and appeared to stimulate bFGF and inhibit TGF-1 secretion (Nowak et al., 2000)

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