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J Neurol 254(12):16761683 Kumar P, Kalonia H, Kumar A (2010) Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntingtons disease
BCX4208 combined with allopurinol increases response rates in patients with gout Who fail to reach goal range serum urate on allopurinol alone: A Randomized, Double-Blind, PlaceboControlled Trial
therefore, these reactions are termed 'idiosyncratic' DILI (IDILI).4 Many drugs have been identified to cause IDILI in humans.5 Antithyroid drugs-induced hepatic injury is categorized as IDILI.6 Due to its high morbidity and mortality, and unpredictable nature, DILI has become a major clinical challenge.7 Moreover, DILI accounts for a large number of drug withdrawals from the marketplace, or discontinuation of further development of a drug candidate