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L., RoyChoudhury, A., & Laferrre, B

Of these three parameters, TxB2 production was significantly reduced at both doses, PDGF release was significantly reduced at 10 mM, and collagen-induced platelet aggregation was not significantly reduced [7]

Since Shh -expressing placode cells generate the majority of cells in hair peg, including those still expressing Shh , this intriguing change in cell fate indicates that progenies of Shh -expressing placode cells separate into two different populations: the population still expressing Shh loose the potential to form HFSCs, while the cells with down regulated Shh expression in hair peg can presumably still become HFSCs

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