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As the NADPH metabolism are shared in normal and cancer cells, selectively targeting NADPH synthesis under special circumstances without affecting normal cells is difficult

Vitamin C and Selenium These nutrients act as "co-factors." Selenium is a mineral that helps the enzyme glutathione peroxidase function, while vitamin C helps "recharge" glutathione once it has spent its antioxidant power

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Additional lawsuits and adverse event reports have described bowel obstruction, ileus, gallbladder disease, gallstones, cyclic vomiting syndrome, and vision-related complications involving optic nerve damage and sudden vision loss