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Mice with Glp1r deletion under the regulation of the Tie2 gene promoter ( Tek ) were generated by crossing Tg(Tek-Cre)1Ywa mice (Tie2-Cre) from The Jackson Laboratory (stock 008863) with Glp1r fl/fl mice (48)

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4 Multimodal integration and translational prospects of zebrafish-driven Building upon the technology-augmented zebrafish framework outlined in Section 3.1, the platform has evolved from a validation tool into a multimodal discovery engine for anti-inflammatory phytomedicines