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Under Dihexa (PNB-0408) stimulation, the hepatocyte growth factor (HGF)/c-Met receptor system can induce dendritic dendrites and synaptogenesis [2]

DHODH holds a pivotal position in the biosynthetic pathway of pyrimidine nucleotides, playing a crucial role in the production of DNA and RNA (49), Inhibition of DHODH disrupts this pathway, leading to abnormalities in, or cessation of, pyrimidine nucleotide synthesis

10.1126/science.1223813 29