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The peptide was originally identified as a fragment derived from human gastric juice and is classified as a body protection compound (BPC)

A2A receptor activation upregulates vascular endothelial growth factor (VEGF), promotes angiogenesis in dermal microvasculature, stimulates fibroblast migration and proliferation, and suppresses inflammatory cytokine release

When adverse effects do occur following high-dose B12 administration, they are typically mild, transient, and often related to the route of administration rather than the vitamin itself