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Your gut and brain are physically connected by the Vagus Nerve

Whilst danuglipron is not available, UK patients can access MHRA-approved GLP-1 treatments such as semaglutide (Wegovy) and liraglutide (Saxenda) through NHS specialist weight management services, subject to NICE eligibility criteria and supply availability

James Hunt, deputy chief executive of CheqUp, talks of a revolution

in Cell Metabolism note that SIRT1 activation improves mitochondrial efficiency and promotes a shift toward lipid utilization for energy, which can be especially beneficial in endurance and fat-loss settings (Price et al., Cell Metabolism )