glp-1 obesity drug market size 2025 Receptor Agonist GLP-1 Receptor Agonist Market Growth

The beneficial effect of tirzepatide on hsCRP, a biomarker of systemic inflammation, YKL-40, a proinflammatory cytokine, and ICAM-1, a biomarker of endothelial dysfunction, was already detectable at 4 weeks, consistent with the salutary effects of GIP and GLP-1 on inflammation and atherosclerosis in experimental models [84,85,86]

Proactive consultation with a GP or diabetes specialist is essential to develop a personalised management plan balancing maternal metabolic health with infant safety

GLP-1 receptor agonists stimulate glucose-dependent insulin secretion and suppress appetite, whilst metformin reduces hepatic glucose production and enhances insulin sensitivity