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Treatment with LC in the MSG + LC 200 group significantly raised the mRNA expressions of Star and Cyp11a1 in comparison with the MSG group ( p = 0.019 and p = 0.01, respectively), while increase in the mRNA expression of Hsd17b3 was not significant

Furthermore, treatment with Schisandra chinensis has been shown to increase the intracellular level of GSH and stimulate its synthesis in hepatocytes

Clinically, Danon disease manifests as cardiomyopathy, skeletal myopathy, and cognitive impairment, with cardiac involvement being the predominant and most life-threatening feature

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