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When confronted with harmful substances such as toxins or byproducts of oxidative stress in the periphery or brain tissue, the vascular system flexibly initiates defensive mechanisms to mitigate potential harm, demonstrating an adaptive response that protects the BBBs protective function

Hortic Plant J 10(3):321334 Wang X, Wang J, Ai W, Zhao N, Zhang Y, Xu L et al (2025b) Transcriptomic and metabolomic analyses uncover the molecular defense strategy of Mikania micrantha under feeding stress from Pachypeltis micranthus