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Deficiency Risks and Who Is Most Affected Certain groups are at higher risk of deficiency, including: Vegetarians and vegans Adults over 50 with reduced stomach acid Patients with gut disorders such as Crohns or celiac disease Those taking long-term acid-reducing medications Symptoms of deficiency can include fatigue, pale skin, memory loss, depression, numbness, or tingling sensations

Several studies have linked B12 deficiency to obesity and a review concluded that B12 deficiency could also lead to a higher percentage of fat accumulation

Low absorption rates due to the digestive process

Factors such as storage conditions, packaging and the type of vitamin can all influence how long supplements remain viable